Largest reasonable single external HD

what largest reasonable external single hard drive setup 2011 imac work with? put own using hard drive enclosure , large 4tb drive?

asking continue thinking ways data, movies, music, , photos. past couple of years have had distributed among several usb hard drives. new imac's 1 tb drive filling consolidate itunes , iphoto.

-=- boris

 

as large can find.

 

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